Im seit 1985 jährlich als Buch erscheinenden Arzneiverordnungs-Report werden die Rezepte für die Patienten der gesetzlichen Krankenversicherung (GKV) mit Methoden der evidenzbasierten Medizin analysiert. Seit dieser Zeit bietet der Report eine unabhängige Informationsmöglichkeit über die verschiedenen Komponenten der Arzneimittelverordnung und trägt damit zur Transparenz des Arzneimittelmarkts, zur Bewertung von Arzneimitteln und zu einer sowohl zweckmäßigen und sicheren evidenzbasierten als auch wirtschaftlichen Arzneitherapie bei.
Medicine Price Surveys, Analyses and Comparisons establishes guidelines for the study and implementation of pharmaceutical price surveys, analyses, and comparisons. Its contributors evaluate price survey literature, discuss the accessibility and reliability of data sources, and provide a checklist and training kit on conducting price surveys, analyses, and comparisons. Their investigations survey price studies while accounting for the effects of methodologies and explaining regional differences in medicine prices. They also consider policy objectives such as affordable access to medicines and cost-containment as well as options for improving the effectiveness of policies. Provides guidance for planning and implementing pharmaceutical pricing policies and systems Reviews external price referencing systems Explains common baselines for interpreting price surveys Defines pharmaceutical price terminology and nomenclature
Periodically in the evolution of an important branch of clinical medicine there develops a critical need for a textbook which combines with the clinical aspects of disease syndromes an in-depth review of the sciences basic to the disorders discussed, as well as a carefully selected but com prehensive review of pertinent literature. LABHART'S Clinical Endo crinology revised and translated into English provides for this need in the field of endocrinology in an exemplary manner. Prof. LABHART has selected his individual authors with great care, and they in turn have provided authoritative monographs. An interesting, useful and informative introduction to each chapter is provided by a tabulation of the dates of important or significant contributions to the field. The chapter subdivisions present in great detail a wide variety of subjects such as embryology, anatomy, biochemistry, physiology, indi vidual hormones and their analogues, biosynthesis, metabolism and regulation of hormone release as well as a full discussion of the clinico pathological correlations. The bibliography is unusually extensive and will provide an important source book for all investigators and students in the field.
This atlas, featuring a wealth of high-quality images, offers a comprehensive overview of therapeutic gastrointestinal endoscopy for upper and lower gastrointestinal diseases. Both established and new therapeutic techniques using advanced endoscopic devices are extensively covered. The concise text accompanying the endoscopic photographs and illustrations will enable readers to understand the details of each procedure. Special tips of practical value are highlighted and potential pitfalls, identified. The authors are experts in the field who have a great store of knowledge on a wide variety of therapeutic endoscopic procedures. Gastrointestinal endoscopy is the principal tool for the investigation and treatment of most diseases of the gastrointestinal tract. This book will provide the clear guidance that practitioners require in order to perform therapeutic gastrointestinal endoscopy optimally; it will prove indispensable for all gastrointestinal endoscopists.
Seit 30 Jahren erscheint der Arzneiverordnungs-Report mit Daten, Analysen und Kommentaren zur Verordnung von Arzneimitteln. Erklärte Ziele des Buches sind seitdem die Transparenz des Arzneimittelmarkts, die Bewertung von Arzneimitteln und die evidenzbasierte Arzneitherapie. Jährlich werden die Rezepte für die Patienten der gesetzlichen Krankenversicherung (GKV) analysiert. 2013 haben 202.965 Vertragsärzte 819 Mio. Arzneiverordnungen im Wert von 32,1 Mrd. € (+3,2%) ausgestellt. Seit 3 Jahren ist die Nutzenbewertung gemäß Arzneimittelmarkt-Neuordnungsgesetz (AMNOG) etabliert. Damit wurde erreicht, dass neue Arzneimittel in Deutschland nicht mehr teurer sind als in den europäischen Nachbarländern.
Prediction models are important in various fields, including medicine, physics, meteorology, and finance. Prediction models will become more relevant in the medical field with the increase in knowledge on potential predictors of outcome, e.g. from genetics. Also, the number of applications will increase, e.g. with targeted early detection of disease, and individualized approaches to diagnostic testing and treatment. The current era of evidence-based medicine asks for an individualized approach to medical decision-making. Evidence-based medicine has a central place for meta-analysis to summarize results from randomized controlled trials; similarly prediction models may summarize the effects of predictors to provide individu- ized predictions of a diagnostic or prognostic outcome. Why Read This Book? My motivation for working on this book stems primarily from the fact that the development and applications of prediction models are often suboptimal in medical publications. With this book I hope to contribute to better understanding of relevant issues and give practical advice on better modelling strategies than are nowadays widely used. Issues include: (a) Better predictive modelling is sometimes easily possible; e.g. a large data set with high quality data is available, but all continuous predictors are dich- omized, which is known to have several disadvantages.
Die vertragsärztlichen Arzneiverordnungen für ambulante Patienten werden seit 1985 im Arzneiverordnungs-Report analysiert. Datenbasis für 2012 sind 716 Millionen GKV-Rezepte (davon 634 Mio. Fertigarzneimittelrezepte), die von 203 599 Vertragsärzten ausgestellt wurden, darunter erstmals auch 60 533 Zahnärzte. In 40 Indikationsgruppen werden aktuelle Versorgungstrends dargestellt. Zum ersten Mal ist auch ein Kapitel über Rezepturarzneimittel enthalten sowie ein zusätzliches Kapitel über zahnärztliche Verordnungen. Presseecho zum Arzneiverordnungs-Report 2012 „Noch viel Luft bei Pharmapreisen ‒ Arzneimittelreport sieht Milliarden-Einsparpotential“ (Frankfurter Allgemeine Zeitung 28.09.2012) „Deutsche zahlen bei Pillen drauf ‒ Untersuchung lobt Reformen, aber warnt vor neuem Ausgabenanstieg“ (Hannoversche Allgemeine Zeitung 28.09.2012) „Die Patienten zahlen drauf ‒ Die Kosten für Arzneimittel gehen wieder nach oben. Das ist ganz im Sinne der Industrie, doch schlecht für die Beitragszahler“ (Sächsische Zeitung 28.09.2012) „Pillenknick ‒ Der Preistopp wirkt: Kosten für Medikamente sinken, obwohl mehr verschrieben werden“ (Süddeutsche Zeitung 28.09.2012)
The Handbook of Research Management is a unique tool for the newly promoted research leader. Larger-scale projects are becoming more common throughout the social sciences and humanities, housed in centres, institutes and programmes. Talented researchers find themselves faced with new challenges to act as managers and leaders rather than as individual scholars. They are responsible for the careers and professional development of others, and for managing interactions with university administrations and external stakeholders. Although many scientific and technological disciplines have long been organized in this way, few resources have been created to help new leaders understand their roles and responsibilities and to reflect on their practice. This Handbook has been created by the combined experience of a leading social scientist and a chief executive of a major international research development institution and funder. The editors have recruited a truly global team of contributors to write about the challenges they have encountered in the course of their careers, and to provoke readers to think about how they might respond within their own contexts. This book will be a standard work of reference for new research leaders, in any discipline or country, looking for help and inspiration. The editorial commentaries extend its potential use in support of training events or workshops where groups of new leaders can come together and explore the issues that are confronting them.
This book examines various applications of electron spin resonance spectroscopy (ESR) in medicine, covering topics such as interactions between blood and nanoparticles, physical intricacy of HbNO complexes, parasitic diseases, oxidative stress measurement, polymerization of resinous materials used in dentistry, tooth dosimetry and dermatological applications. Instead of providing mathematical details, it focuses on the applications and data interpretation of ESR as an emerging tool. This book is intended for students and researchers interested in the field of ESR applications in translational research and medicine.
This fully updated 4th Edition of provides an integrated symptom- and issue-based approach with easy access to high yield clinical information. For each topic, carefully organized sections on different diagnoses, investigations, and treatments are designed to facilitate patient care and examination preparation. Numerous clinical pearls and comparison tables are provided to help enhance learning, and international units (US and metric) are used to facilitate application in everyday clinical practice. The book covers many highly important, rarely discussed topics in medicine (e.g., smoking cessation, obesity, transfusion reactions, needle stick injuries, code status discussion, interpretation of gram stain, palliative care), and new chapters on end-of-life care and depression have been added. The fourth edition includes many reader-friendly improvements such as better formatting, intuitive ordering of chapters, and incorporation of the most recent guidelines for each topic. Approach to Internal Medicine continues to serve as an essential reference for every medical student, resident, fellow, practicing physician, nurse, and physician assistant.
This book informs and supports medical educators and clinic leaders regarding the key clinical and administrative components necessary to run an academic medical practice. From a group of expert faculty from the Society of General Internal Medicine (SGIM) with years of experience in managing academic medical practices, this manual offers comprehensive guidance to the clinic director regarding critical factors involved with running an academic medical practice including, but not limited to: compliance with Accreditation Council for Graduate Medical Education (ACGME) requirements, clinic orientation and curricula implementation, clinic workflow challenges, billing, coding, and the Primary Care Exception Rule, productivity metrics and quality indicators, evaluation and feedback for trainees, faculty, and clinic staff, implementation of a Patient Centered Medical Home (PCMH), development of controlled substance prescribing policies, medical student involvement in resident clinics, and Veteran Affairs practices and non-traditional care settings. The scope of this book is sufficiently broad to be comprehensive and practical while still anticipating the further evolution of the academic medical practice in the years to come. Each chapter focuses on a particular aspect of clinic leadership and will offer real-world examples and management “pearls” for the clinic director. Chapters highlight common challenges and solutions and should be useful across disparate practice settings. This is an ideal resource for clinic directors, core faculty, and clinic leadership in academic outpatient medical practices, particularly those within the field of Internal Medicine, Primary Care, and related specialties.
The second edition of this very popular atlas is designed to serve as an up-to-date guide to the diagnostic use of gastrointestinal endoscopy that will meet the daily needs of both novice and advanced endoscopists. The atlas presents an abundance of typical and atypical endoscopic images of common and rare diseases of the esophagus, stomach, small intestine, and colorectum, accompanied by precise clinical descriptions. Normal findings and variants are also amply documented. A large majority of the illustrations in the new edition are superb high-resolution images, reflecting the important advances of recent years. The coverage also includes the role of novel endoscopic technologies such as narrow band imaging, FICE, iScan, and confocal laser endomicroscopy. A further new feature is the inclusion of an interesting quiz at the end of each chapter in order to summarize complex knowledge, enhance understanding, and assist in the internalization of important practical tips. Clinical Gastrointestinal Endoscopy: A Comprehensive Atlas is expected to become the ultimate reference for gastrointestinal endoscopists worldwide.
The definitive textbook on the use of lithium in the treatment of mental disorders, this comprehensive work provides an up-to-date analysis of lithium, including: History Clinical applications, including its use for mania, bipolar and schizophrenic disorders Use in special populations, for example in children, the elderly and people with medical conditions The effect on the body and behavior, including neurological, gastrointestinal, cardiovascular and dermatological effects, as well as those relating to the kidneys and thyroid Basic findings in pharmacology, chemistry, transport in the body, pharmacokinetics, signal transduction pathways, immune function, gene regulation. Practical issues, such as guidelines for safe use, discontinuation issues, compliance, intoxication, and economics. Edited by top experts from the International Group for the Study of Lithium Treated Patients (IGSLi), Lithium in Neuropsychiatry: A Comprehensive Guide is a unique and vital resource for psychiatrists, psychopharmacologists, psychotherapists and neuroscientists.
In a world where there is increasing demand for the performance of health providers to be measured, there is a need for a more strategic vision of the role that performance measurement can play in securing health system improvement. This volume meets this need by presenting the opportunities and challenges associated with performance measurement in a framework that is clear and easy to understand. It examines the various levels at which health system performance is undertaken, the technical instruments and tools available, and the implications using these may have for those charged with the governance of the health system. Technical material is presented in an accessible way and is illustrated with examples from all over the world. Performance Measurement for Health System Improvement is an authoritative and practical guide for policy makers, regulators, patient groups and researchers.
In 1996 the Institute of Medicine launched the Quality Chasm Series, a series of reports focused on assessing and improving the nation's quality of health care. Preventing Medication Errors is the newest volume in the series. Responding to the key messages in earlier volumes of the series-To Err Is Human (2000), Crossing the Quality Chasm (2001), and Patient Safety (2004)-this book sets forth an agenda for improving the safety of medication use. It begins by providing an overview of the system for drug development, regulation, distribution, and use. Preventing Medication Errors also examines the peer-reviewed literature on the incidence and the cost of medication errors and the effectiveness of error prevention strategies. Presenting data that will foster the reduction of medication errors, the book provides action agendas detailing the measures needed to improve the safety of medication use in both the short- and long-term. Patients, primary health care providers, health care organizations, purchasers of group health care, legislators, and those affiliated with providing medications and medication- related products and services will benefit from this guide to reducing medication errors.
The Fifth Edition of Luellmann's Color Atlas of Pharmacology has been extensively revised to include all recent advances and new drugs, and the illustrations have been optimized and updated. Each two-page spread presents concise text on the left complemented by detailed full-color illustrations on the right to help users quickly digest important facts and concepts. Color-coded sections provide readers with a helpful framework with which to approach the latest developments in pharmacology. Part 1, General Pharmacology, explains basic aspects, such as drug absorption, distribution, and elimination, along with the molecular mechanisms of drug actions Part 2, Systems Pharmacology, presents the different groups of drugs, emphasizing their functional and therapeutic aspects Part 3, Therapy of Selected Diseases, provides all the relevant information regarding the pharmacological treatment of a large number of conditions Key features: User-friendly format ideal for study and review, self-assessment, and quick reference Completely revised and updated, with 174 color plates New glossary of important and interesting pharmacological terms Updated detailed drug indexes containing current information on drugs listed by both generic and brand names The Fifth Edition of Color Atlas of Pharmacology is an essential study guide and reference for every student, nurse, and practicing physician needing to keep up to date with recent advances in the field.
Now thoroughly up-to-date, Clinical Gastrointestinal Endoscopy, 3rd Edition, by Drs. Vinay Chandrasekhara, Mouen Khashab, B. Joseph Elmunzer, and V. Raman Muthusamy, ensures that you stay current with the latest technology and techniques in GI endoscopy. An all-new editorial team, newly updated images, and a reorganized format make this reference an easy-to-use source of reliable information on a full range of topics, including anatomy, pathophysiology, and therapeutic management options, in addition to the latest GI procedures and technologies. Features 1,000 revised photographs, endoscopic images, and anatomical drawings. Provides a fresh perspective and expert guidance from an entirely new editorial team. Includes many more references per chapter. Presents material in a newly restructured, organ-based format for quick reference.
Vincent Bugliosi, whom many view as the nation's foremost prosecutor, has successfully taken on, in court or on the pages of his books, the most notorious murderers of the last half century--Charles Manson, O.J. Simpson, and Lee Harvey Oswald. Now, in the most controversial book of his celebrated career, he turns his incomparable prosecutorial eye on the greatest target of all: God. In making his case for agnosticism, Bugliosi has very arguably written the most powerful indictment ever of God, organized religion, theism, and atheism. Theists will be left reeling by the commanding nature of Bugliosi's extraordinary arguments against them. And, with his trademark incisive logic and devastating wit, he exposes the intellectual poverty of atheism and skewers its leading popularizers--Christopher Hitchens, Sam Harris, and Richard Dawkins. Joining a 2,000-year-old conversation which no one has contributed anything significant to for years, Bugliosi, in addition to destroying the all-important Christian argument of intelligent design, remarkably--yes, scarily--shakes the very foundations of Christianity by establishing that Jesus was not born of a virgin, and hence was not the son of God, that scripture in reality supports the notion of no free will, and that the immortality of the soul was a pure invention of Plato that Judaism and Christianity were forced to embrace because without it there is no life after death. Destined to be an all-time classic, Bugliosi's Divinity of Doubt sets a new course amid the explosion of bestselling books on atheism and theism--the middle path of agnosticism. In recognizing the limits of what we know, Bugliosi demonstrates that agnosticism is he most intelligent and responsible position to take on the eternal question of God's existence.