Evidence-Based Diagnosis explains diagnostic, screening, and prognostic tests in clinical medicine. The authors' approach is based on many years of experience teaching physicians in a clinical research training program. Although needing only a minimum of mathematics, the quantitative discussions in this book are deeper and more rigorous than in most introductory texts. The book includes numerous worked examples and 60 problems (with answers) based on real clinical situations and journal articles. This book is a great choice for anyone looking to select, develop, or apply medical tests. Topics covered include: the diagnostic process; test reliability and accuracy; testing and treatment thresholds; critical appraisal of studies of diagnostic, screening and prognostic tests; test independence and methods of combining tests; quantifying treatment benefits using randomized trials and observational studies; Bayesian interpretation of P values and confidence intervals; challenges for evidence-based diagnosis; likelihood ratios and ROC curves.
British Medical Association Book Awards 2009 - First Prize Winner, Primary Care Category Evidence-Based Diagnosis in Primary Care provides guidance on diagnosis in general practice, from the patient’s first presentation with a symptom to the final establishment of a diagnosis or referral for further investigation. The book is divided into two parts: • Symptoms; which details the steps necessary to reach a provisional diagnosis when a patient presents; and • Disorders; in which the more detailed assessment of that initial diagnosis is described. This is the first book to be written about diagnosis in primary care that attempts to base its guidance on the research evidence. Enough information is provided on each symptom, or condition, to decide on the pre-test probability of each possible disorder, and how the symptoms, signs and investigations alter those probabilities to allow a conclusion to be reached about the most likely diagnosis. Evidence-Based Diagnosis in Primary Care also explains the principles of evidence-based diagnosis – with special emphasis on the issues raised by attempting an evidence-based approach in primary care – and clearly demonstrates the power, and the difficulties, of an evidence-based approach. Many chapters also feature ‘red flags’ – elements of the history or examination that should alert the practitioner to the possibility of serious disease, which is vital for general practice.
Covering a full range of topics from cardiovascular and pulmonary disease to ophthalmology, hematology and pediatrics, this is the only single volume, quick reference designed for use in daily practice. The 150+ clinical prediction rules as well as the background information necessary to determine its validity and relevance are essential for every physician in a time of limited health care resources. Designed as an aid in diagnosis and treatment, these rules allow more accurate diagnosis and treatment decisions while eliminating superfluous testing.
Fully updated from cover to cover, incorporating over 200 new studies on the evidence-based approach to diagnosis, the 4th Edition of Evidence-Based Physical Diagnosis remains your go-to resource for guidance on interpreting physical signs, enabling you to determine the most appropriate physical finding to confirm a diagnosis. Internationally renowned author Dr. Steven McGee puts the most current evidence at your fingertips, allowing you to quickly compare all physical signs for a given diagnosis, understand their significance, and then select the most accurate ones. Includes a unique evidence-based calculator online that enables you to easily determine probability using likelihood ratios. Features a reader-friendly outline format, including dozens of "EBM boxes" and accompanying "EBM ruler" illustrations. Provides new evidence on the scientific value of many physical findings, including Cheyne-Stokes respirations, subclavian stenosis, fever of unknown origin, porto-pulmonary hypertension, localization of stroke, and many more. NEW Key Teaching Points at the beginning of every chapter, ideal for teachers of bedside medicine.
An authoritative guide to clinical management of women with known or suspected coronary artery disease. Using an evidence-based approach, the authors apply the latest epidemiological findings and diagnostic tools to the evaluation of stable chest pain and acute ischemic syndromes in women, and detail the therapeutic effectiveness of various treatments in women, such as coronary revascularization, electrophysiology, exercise training and cardiac rehabilitation, and menopausal hormone therapy. Additional chapters examine the effects of gender bias in diagnosis and treatment, the role of gynecologists as primary care physicians for women, health technology assessment in an era of managed care, and the problems of analyzing cost-effectiveness in the diagnosis and treatment of coronary artery disease in women.
This unique book presents a framework for the strategy and methodology of diagnostic research, in relation to its relevance for practice. Now in its second edition The Evidence Base of Clinical Diagnosis has been fully revised and extended with new chapters covering the STARD guidelines (STAndards for the Reporting of Diagnostic accuracy studies) and the multivariable analysis of diagnostic data. With contributions from leading international experts in evidence-based medicine, this book is an indispensable guide on how to conduct and interpret studies in clinical diagnosis. It will serve as a valuable resource for all investigators who want to embark on diagnostic research and for clinicians, practitioners and students who want to learn more about its principles and the relevant methodological options available.
Learn the diagnostic process in internal medicine with this engaging, case-based approach Symptom to Diagnosis teaches you an evidence-based, step-by-step process for evaluating, diagnosing, and treating patients based on their clinical complaints. By applying this process, you will be able to recognize specific diseases and prescribe the most effective therapy. Each chapter addresses one common complaint and begins with a case and guidance on how to organize the differential diagnosis. As the case progresses, clinical reasoning is explained in detail. The differential diagnosis for that particular case is summarized in tables that highlight the clinical clues and important tests for the leading diagnostic hypothesis and alternative diagnostic hypotheses. As the chapter progresses, the pertinent diseases are reviewed. Just as in real life, the case unfolds in a stepwise fashion as tests are performed and diagnoses are confirmed or refuted. The third edition is enhanced by the addition of five new chapters--Bleeding Disorders, Dysuria, Hematuria, Hypotension, and Sore Throat--as well as a greater emphasis on how to master the process of working from patient level data (signs, symptoms, and laboratory tests). All chapters incorporate the latest research resulting in new and refined approaches to common symptoms encountered in clinical medicine.
Now in its fourth edition, Rational Diagnosis and Treatment: Evidence-Based Clinical Decision-Making is a unique book to look at evidence-based medicine and the difficulty of applying evidence from group studies to individual patients. The book analyses the successive stages of the decision process and deals with topics such as the examination of the patient, the reliability of clinical data, the logic of diagnosis, the fallacies of uncontrolled therapeutic experience and the need for randomised clinical trials and meta-analyses. It is the main theme of the book that, whenever possible, clinical decisions must be based on the evidence from clinical research, but the authors also explain the pitfalls of such research and the problems involved in applying evidence from groups of patients to the individual patient. For this new edition, the sections on placebo and meta-analysis and on alternative medicine have been thoroughly updated, and there is more focus on insufficient reporting of harms of interventions. The sections on different research designs describe advantages and limitations, and the increased medicalisation and the effects of cancer screening on health people are noted. A section on academic freedom when clinicians collaborate with industry and ghost authors is added. This essential reference work integrates the science and statistical approach of evidence-based medicine with the art and humanism of medical practice; distinguishing between data, sets of data, knowledge and wisdom, and their application. Such an intellectually challenging book is ideal for both medical students and doctors who require theoretical and practical clinical skills to help ensure that they apply theory in practice.
This small pocket book contains more than 500 clinical pearls in 12 major areas of internal medicine, collected from teaching conferences for residents at the Johns Hopkins Hospital. The pearls were selected by two residents and reviewed by senior faculty at the Johns Hopkins University School of Medicine.
"The purpose of this book is to present relevant questions on diagnostic testing that arise in everyday emergency medicine practice and to comment on the best available evidence"--Provided by publisher.
The ultimate guide to the evidence-based clinical encounter "This book is an excellent source of supported evidence that provides useful and clinically relevant information for the busy practitioner, student, resident, or educator who wants to hone skills of physical diagnosis. It provides a tool to improve patient care by using the history and physical examination items that have the most reliability and efficiency."--Annals of Internal Medicine "The evidence-based examination techniques put forth by Rational Clinical Examination is the sort that can be brought to bear on a daily basis – to save time, increase confidence in medical decisions, and help decrease unnecessary testing for conditions that do not require absolute diagnostic certainty. In the end, the whole of this book is greater than its parts and can serve as a worthy companion to a traditional manual of physical examination."--Baylor University Medical Center (BUMC)Proceedings 5 STAR DOODY'S REVIEW! "Physical diagnosis has been taught to every medical student but this evidence-based approach now shows us why, presenting one of medicine's most basic tenets in a new and challenging light. The format is extraordinary, taking previously published material and updating the pertinent evidence since the initial publication, affirming or questioning or refining the conclusions drawn from the data. "This is a book for everyone who has studied medicine and found themselves doubting what they have been taught over the years, not that they have been deluded, but that medical traditions have been unquestionably believed because there was no evidence to believe otherwise. The authors have uncovered the truth. "This extraordinary, one-of-a-kind book is a valuable addition to every medical library."--Doody's Review Service Completely updated with new literature analyses, here is a uniquely practical, clinically relevant approach to the use of evidence in the content of physical examination. Going far beyond the scope of traditional physical examination texts, this invaluable resource compiles and presents the evidence-based meanings of signs, symptoms, and results from physical examination maneuvers and other diagnostic studies. Page after page, you'll find a focus on actual clinical questions and presentations, making it an incomparably practical resource that you'll turn to again and again. Importantly, the high-yield content of The Rational Clinical Examination is significantly expanded and updated from the original JAMA articles, much of it published here for the first time. It all adds up to a definitive, ready-to-use clinical exam sourcebook that no student or clinician should be without. FEATURES Packed with updated, new, and previously unpublished information from the original JAMA articles Standardized template for every issue covered, including: Case Presentation; Why the Issue Is Clinically Important; Research and Statistical Methods Used to Find the Evidence Presented; The Sensitivity and Specificity of Each Key Result; Resolution of the Case Presentation; and the Clinical Bottom Line Completely updated with all-new literature searches and appraisals supplementing each chapter Full-color format with dynamic clinical illustrations and images Real-world focus on a specific clinical question in each chapter, reflecting the way clinicians approach the practice of evidence-based medicine More than 50 complete chapters on common and challenging clinical questions and patient presentations Also available: JAMAevidence.com, a new interactive database for the best practice of evidence based medicine
This multidisciplinary textbook presents a unique approach to diagnosis and management of the various temporomandibular disorders. Written by a large group of eminent researchers and clinicians, it links current scientific concepts of basic anatomy, physiology, biomechanics, and pathology of the temporomandibular joint with specific diagnostic and treatment protocols that are based on sound clinical data. Thus, in keeping with the current thrust in medicine and dentistry, the book provides access to the best available evidence so that clinicians can make informed rather than empirical decisions about what is appropriate therapy. Where lack of data or rapid changes in a particular discipline do not allow for evidence-based conclusions or recommendations, the book highlights the areas of agreement and disagreement in order to expose the deficiencies in our present knowledge base. In a field of treatment long associated with controversy, this book educates readers about which current practices of diagnosis and treatment are strongly supported by scientific research and which are supported only by practical experience and/or anecdotal evidence.
The definitive evidence-based introduction to patient history-taking NOW IN FULL COLOR For medical students and other health professions students, an accurate differential diagnosis starts with The Patient History. The ideal companion to major textbooks on the physical examination, this trusted guide is widely acclaimed for its skill-building, and evidence based approach to the medical history. Now in full color, The Patient History defines best practices for the patient interview, explaining how to effectively elicit information from the patient in order to generate an accurate differential diagnosis. The second edition features all-new chapters, case scenarios, and a wealth of diagnostic algorithms. Introductory chapters articulate the fundamental principles of medical interviewing. The book employs a rigorous evidenced-based approach, reviewing and highlighting relevant citations from the literature throughout each chapter. Features NEW! Case scenarios introduce each chapter and place history-taking principles in clinical context NEW! Self-assessment multiple choice Q&A conclude each chapter—an ideal review for students seeking to assess their retention of chapter material NEW! Full-color presentation Essential chapter on red eye, pruritus, and hair loss Symptom-based chapters covering 59 common symptoms and clinical presentations Diagnostic approach section after each chapter featuring color algorithms and several multiple-choice questions Hundreds of practical, high-yield questions to guide the history, ranging from basic queries to those appropriate for more experienced clinicians
This is the first neuropsychology book to translate exciting findings from the recent explosion of research on sport-related concussion to the broader context of mild traumatic brain injury (MTBI) and post-concussive syndrome (PCS) in the general population. In addition, it includes a Continuing Education (CE) component administered by the American Academy of Clinical Neuropsychology. Traumatic brain injuries constitute a major global public health problem, but until now, MTBIs, which constitute up to 90 percent of all treated TBIs, have been difficult to evaluate and manage clinically because of the absence of a viable model. Dr. McCrea's book thus provides a welcome evidence base for all clinicians - including psychologists, neuropsychologists, neurologists, neurosurgeons, rehabilitation medicine physicians, physiatrists, and nurses - involved in the clinical diagnosis and treatment of MTBI, as well as attorneys involved in personal injury litigation and personal injury defense. Each section of the book ends with a helpful summary of the 'Top 10 Conclusions.' Instructions for earning AACN-administered CE credit are included.
Nelson Pediatric Symptom-Based Diagnosis uses a unique, step-by-step, symptom-based approach to differential diagnosis of diseases and disorders in children and adolescents. Conveniently linked to the world’s best-selling pediatric reference, Nelson Textbook of Pediatrics, 20th Edition, it focuses on the symptoms you’re likely to see in general practice, as well as uncommon disorders. You’ll find clear guidance on exactly what to consider and how to proceed when faced with a host of common symptoms such as cough, fever, headache, chest pain, gait disturbances, and many more. Features a practical, symptom-based approach that enables you to form an accurate diagnosis. Uses the same consistent, step-by-step presentation in every chapter: History, Physical Examination, Diagnosis (including laboratory tests), Imaging, Diagnosis, and Treatment. Covers new approaches to diagnostic imaging and genetic testing, new diagnostic guidelines, BRUE (brief resolved unexplained event), stroke in children, behavior disorders, syncope, recurrent fever syndromes, and much more. Includes full-color illustrations, algorithms, tables, and "red flags" to aid differential diagnosis. Serves as an ideal companion to Nelson Textbook of Pediatrics, 20th Edition.
First book dedicated to this disease, previously thought to be incurable, but with the advent of new drugs, now amenable to management and a much improved prognosis for patients From the PAH Association, the leading experts in field Incorporates the latest AACP management guidelines Includes evidence-based treatment algorithms based on the recently updated ACCP Guidelines for Medical Treatment Aimed at specialists in pulmonology and cardiovascular disease, this volume provides the clinician with the most up to date information on the effective management of PAH
An engaging case-based approach to learning the diagnostic process in internal medicine "All clinicians caring for patients, from medical students to residents and attending physicians, are the intended audience. The book is well written for all levels, and the authors are well-respected educators and experts in the field. 3 Stars."--Doody's Review Service Symptom to Diagnosis teaches you an evidence-based, step-by-step process for evaluating, diagnosing, and treating patients based on their clinical complaints. By applying this process you will be able to recognize specific diseases and prescribe the most effective therapy. Each chapter is built around a common patient complaint that illustrates essential concepts and provides insight into the process by which the differential diagnosis is identified. Coverage for each disease includes: Textbook Presentation: offers a concise statement of the common or classic presentation of the particular disease Disease Highlights: covers the most pertinent epidemiologic and pathophysiologic information for the disease Evidence-Based Diagnosis: reviews the accuracy of the history, physical exam, laboratory and radiologic tests for the disease. In this unique section, the author points out the findings that help you “rule in” or “rule out” the various diseases. Treatment: details the basics of therapy for the disease discussed Filled with algorithms, summary tables, and questions that direct evaluation, Symptom to Diagnosis is a true must read before your first clinical encounter.
Written by a group of renowned experts three decades after the publication of the last comprehensive book on this topic, this much-needed book has a wealth of evidence-based information on all facets of the restoration of pulpless teeth. With a better understanding of the factors that can influence the prognosis of severely compromised teeth, the approach to treating these teeth has evolved, and this text offers a well-balanced, contemporary approach to treatment planning. Traditional principles and techniques are reviewed and reinforced, along with modern materials and methods, all with a firm foundation in the best available scientific evidence and with an emphasis on clinical studies. Many of the chapters provide comprehensive, step-by-step descriptions of technical procedures with accompanying illustrations to guide the reader through every stage of restoring pulpless teeth, including fabrication of various foundation restorations, cementation techniques, and methods of provisionalization. Preprosthetic adjunctive procedures, such as surgical crown lengthening, repair of perforations, and orthodontic measures, are also described and illustrated. For years to come, this text will remain a definitive reference for specialists involved in the restoration of pulpless teeth or engaged in planning treatment for structurally compromised teeth.
Evidence-Based Neuroimaging is a user-friendly guide that employs evidence-based medicine criteria to systematically review the evidence defining the appropriate use of medical imaging for the brain, spine, head, and neck. Edited by L. Santiago Medina, Pina C. Sanelli, and Jeffrey G. Jarvik, the book provides a systematic framework for understanding the best imaging choices for patient care. Chapters highlight key points that support clinical applications, allowing fast access to pertinent information including patient selection, imaging strategies, test performance, cost-effectiveness, and applicability. The diagnostic imaging of many common diseases, disorders, and conditions are covered, including multiple sclerosis, acute ischemic stroke, dementia, Alzheimer’s disease, traumatic brain injury, autism, spinal trauma, spinal infections, neck masses, thyroid cancer, and cervical lymph node metastasis. By offering a clear understanding of the science behind the evidence, the book fills a void for radiologists, neurologists, neurosurgeons, pediatricians, primary care physicians, and other clinicians with an interest in neuroimaging and a desire to implement an evidence-based approach into their daily practice.
Includes NEW! 4 Color text; updated 2012-2014 NANDA-I approved nursing diagnoses; the latest NIC/NOC, interventions, and rationales for every care plan; the latest NIC/NOC, interventions, and rationales for every care plan; QSEN Safety interventions and rationales; 100 NCLEX exam-style review questions are available on the companion Evolve website; Root Causing Thinking and Motivational Interviewing appendixes on the companion Evolve website.