Visit Armand Marie Leroi on the web: http://armandleroi.com/index.html Stepping effortlessly from myth to cutting-edge science, Mutants gives a brilliant narrative account of our genetic code and the captivating people whose bodies have revealed it—a French convent girl who found herself changing sex at puberty; children who, echoing Homer’s Cyclops, are born with a single eye in the middle of their foreheads; a village of long-lived Croatian dwarves; one family, whose bodies were entirely covered with hair, was kept at the Burmese royal court for four generations and gave Darwin one of his keenest insights into heredity. This elegant, humane, and engaging book “captures what we know of the development of what makes us human” (Nature).
A study of congenital disease and some of the famous individuals whose lives were affected by congenital abnormalities offers insight to mankind's evolutionary history.
Stepping effortlessly from myth to molecular biology, this elegant, humane, and illuminating book explores the myths and fantasies associated with mutants and their critical link to human development.
Combining science, history, and culture, explores every aspect of human anatomy from ancient body art to modern plastic surgery, discussing why some people are left-handed and why some cultures think the soul resides in the liver.
A collection of essays discussing historical medical oddities like spontaneous combustion and tailed people, offering a likely cause for the condition, and mentioning some real human oddities
Speculating that one out of a hundred people were buried alive a century ago, this fascinating book uses folklore, history, and literature to explore the nineteenth-century fears associated with this disturbing fact. Reprint.
A brilliant study of Aristotle as biologist The philosophical classics of Aristotle loom large over the history of Western thought, but the subject he most loved was biology. He wrote vast volumes about animals. He described them, classified them, told us where and how they live and how they develop in the womb or in the egg. He founded a science. It can even be said that he founded science itself. In The Lagoon, acclaimed biologist Armand Marie Leroi recovers Aristotle’s science. He revisits Aristotle’s writings and the places where he worked. He goes to the eastern Aegean island of Lesbos to see the creatures that Aristotle saw, where he saw them. He explores Aristotle’s observations, his deep ideas, his inspired guesses—and the things he got wildly wrong. He shows how Aristotle’s science is deeply intertwined with his philosophical system and reveals that he was not only the first biologist, but also one of the greatest. The Lagoon is both a travelogue and a study of the origins of science. And it shows how a philosopher who lived almost two millennia ago still has so much to teach us today. From the Hardcover edition.
Originally published in hardcover in 2006.
Presents an assortment of bizarre and disgusting facts about the human body organized into sections by anatomical system.
Tells the story of human development from egg to adult, showing how the understanding of how human beings come to be has been transformed in recent years.
As the amount of information in biology expands dramatically, it becomes increasingly important for textbooks to distill the vast amount of scientific knowledge into concise principles and enduring concepts.As with previous editions, Molecular Biology of the Cell, Sixth Edition accomplishes this goal with clear writing and beautiful illustrations. The Sixth Edition has been extensively revised and updated with the latest research in the field of cell biology, and it provides an exceptional framework for teaching and learning. The entire illustration program has been greatly enhanced.Protein structures better illustrate structure–function relationships, icons are simpler and more consistent within and between chapters, and micrographs have been refreshed and updated with newer, clearer, or better images. As a new feature, each chapter now contains intriguing openended questions highlighting “What We Don’t Know,” introducing students to challenging areas of future research. Updated end-of-chapter problems reflect new research discussed in the text, and these problems have been expanded to all chapters by adding questions on developmental biology, tissues and stem cells, pathogens, and the immune system.
The human head is exceptional. It accommodates four of our five senses, encases the brain and boasts the most expressive set of muscles in the body. It is our most distinctive attribute and it connects our inner selves to the outer world more intensely than any other part of the body. Yet there is a dark side to the head's pre-eminence, one that has, in the course of Western history, manifested itself in everything from decapitation to headhunting. Over the centuries, human heads have decorated our churches, festooned our city walls and filled our museums. Long-regarded as objects of fascination and repulsion, they have been props for portrait artists and specimens for laboratory scientists, trophies for soldiers and items of barter.From the western collectors whose demand for shrunken heads spurred brutal massacres, to the Second World War soldiers who sent the remains of Japanese opponents home to their girlfriends; from the memento mori in Romantic portraits to Damien Hirst's platinum skull set with diamonds; from grave-robbing phrenologists to skull-obsessed scientists, Larson explores the bizarre, fantastical and confounding history of the severed head, and offers us a new perspective on our macabre preoccupations.
'The World of Deaf Infants' presents the results of a 15 year research study that has explored the impact of infant deafness on infant development & on the families that support these children.
The internationally acclaimed story of Hannah's Heirs now resumes in this updated paperback edition with the discovery in June, 1995 of Hannah's gene--now known to account for the majority of mutations causing early onset familial Alzheimer's disease--and the equally important identification of the major genetic risk factor rendering increased susceptibility to the more frequently occurring late-onset Alzheimer's. With these recent discoveries, medical science is now poised to reach for an understanding of the causes of the various forms of Alzheimer's disease which, in turn, will inevitably lead to rational attempts to treat and prevent Alzheimer's. This fascinating medical detective story of modern science's promising assault on "the disease of the century" continues to unfold with suspense and to inform and inspire through the final word. In Hannah's Heirs, neurologist Dr. Dan Pollen himself tells the compelling story of Hannah's family and their monumental contributions to the fight against Alzheimer's. We are there in 1985 when Charles presents Pollen with three decades' worth of family medical records as well as data from studies that even Pollen and his associates did not then know existed. We see the selfless acts of Hannah's descendants in their struggle against Alzheimer's: great-grandson Jeff's conviction that after his death his brain be used for all possible research; great-granddaughter Lucy's decision to overcome her dread of flying in order to reach the research center for testing; and Charles's continued research in the face of a disease that might strike him at any moment. Pollen sets this gripping story within the larger context of the efforts to solve the mysteries of Alzheimer's. He presents the foundations of modern genetic research, from Gregor Mendel's classic discovery of genes, to Alois Alzheimer's work on the brains of presenile dementia victims, to Watson and Crick's double helix model for the structure of DNA. He narrates the latter-twentieth-century efforts of scientists to systematically narrow down the causes of Alzheimer's: Carlton Gajdusek's research excluding slow viruses as a cause of Alzheimer's; and the stunning discovery of Peter St. George-Hyslop's group in Toronto in June, 1995 identifying Hannah's gene and thereby opening a new era in understanding the origins of Alzheimer's disease. At the same time, Pollen offers a penetrating look at the ongoing conflicts involved in scientific research, revealing how intense competition for prestige and funding has driven some scientists to hoard precious cell lines. These practices have impeded efforts to discover both the causes and the treatment of Alzheimer's in the shortest possible time. As Hannah's great-grandson Ben has written, "This is a story that had to be told. Aspirations were transcendent, but because it involved people it could not be told without tears." Written by a physician-scientist who has been a central figure in the study of familial Alzheimer's, Hannah's Heirs is an inspiring portrait of the efforts of a courageous family to confront and overcome a "personal biological Holocaust," and an encouraging look at the advances in science that have created the basis for the eventual understanding and treatment of Alzheimer's disease. And for those who have seen the horrors of Alzheimer's, for all who fear the aging process that will take its toll on everyone, here is an inside look at one of the great medical detective stories of our time.
FREAK BABYLON is a sometimes startling, sometimes disturbing documentary of the history of one of mankind's most fascinating sciences - teratology - and its dubious cultural correlative, the Freakshow, from ancient times to the present day. The book features over 200 rare and intriguing photos of human anomalies and covers the areas of scientific research, sideshows, cinema and body modification. By tracing the history of teratology - the classification of human anomalies - and looking at some famous case histories such as the Elephant Man and Johnny Eck, FREAK BABYLON shows how medical research and exploitation are often interlinked - and poses the question whether new sciences of cloning and genetic engineering are taking us back to the "dark days" of man-made freaks. Bonus features include: "The Elephant Man" by Sir Frederick Treves. Long out-of-print, this is the true account which inspired David Lynch's film of the same name. "Dissection of a Symelian Monster" by R C Benington. A classic illustrated account of an autopsy on a real-life human anomaly, from 1891 medical journals. An in-depth illustrated review of the controversial 1932 horror film Freaks, directed by Tod Browning. Tod Robbins' classic short story "Spurs," which inspired Browning's Freaks.
Profiles some two hundred lesser-known figures from the heyday of the American sideshow, tracing the lives of such individuals as legless acrobat Eli Bowen, four-legged woman Myrtle Corbin, and "human torso" Prince Randian, in an account of the rise and fall of sideshows and how advances in modern medicine have enabled voluntary body changes. Reprint.
Handbook of the Aging Brain brings together diverse scientific disciplines to cover the most recent research findings in an easy-to-read summary. Scientists and clinicians will find a wide spectrum of subjects including gerontology, neurology, psychology, molecular biology, and cellular biology. The book includes general chapters on the neuroanatomy and neurobiology of the aging brain, and moves on to discussion of specifics including signal transduction, cell death, and specific cellular and neurological changes associated with dementia, Alzheimer's and Parkinson's Disease. Other chapters discuss the affect of aging on learning and memory, language, and cognition.
Presents an introduction to evolutionary developmental biology which studies genes and their role in biological diversity and evolution.
How does one make decisions today about in vitro fertilization, abortion, egg freezing, surrogacy, and other matters of reproduction? This book provides the intellectual and emotional intelligence to help individuals make informed choices amid misinformation and competing claims. Scott Gilbert and Clara Pinto-Correia speak to the couple trying to become pregnant, the woman contemplating an abortion, and the student searching for sound information about human sex and reproduction. Their book is an enlightening read for men as well as for women, describing in clear terms how babies come into existence through both natural and assisted reproductive pathways. They update “the talk” for the twenty-first century: the birds, the bees, and the Petri dishes. Fear, Wonder, and Science in the New Age of Reproductive Biotechnology first covers the most recent and well-grounded scientific conclusions about fertilization and early human embryology. It then discusses the reasons why some of the major forms of assisted reproductive technologies were invented, how they are used, and what they can and cannot accomplish. Most important, the authors explore the emotional side of using these technologies, focusing on those who have emptied their emotions and bank accounts in a valiant effort to conceive a child. This work of science and human biology is informed by a moral concern for our common humanity.
This text explores human biological variation in its broadest sense - from the molecular to the physiological and morphological - focusing on the micro-evolutionary analysis of genetic variation among recent human populations. Authoritative yet accessible, Human Biological Variation, Second Edition, opens with an engaging introduction to basic genetics and the evolutionary forces that set the stage for understanding human diversity. It goes on to offer a clear and detailed discussion of molecular genetics, including its uses and its relationship to anthropological and evolutionary models. The text features up-to-date discussions of classic genetic markers (blood groups, enzymes, and proteins) along with extensive background on DNA analysis and coverage of satellite DNA, single nucleotide polymorphisms (SNPs), and Alu inserts. Coverage includes current issues such as the meaning and significance of "race," quantitative genetics and the "nature versus nurture" debates, biocultural interactions, population structure, and cultural and historical influences on patterns of human variation. Integrating real-world examples on interesting topics - including dyslexia, IQ, and homosexuality - this second edition of Human Biological Variation provides the most thorough and contemporary view of our biological diversity.