An introduction to oral biology which elaborates selected aspects of the basic sciences as they concern dentistry. Part One introduces anatomy, endocrinology, histology, physiology, biochemistry and genetics and Part Two brings these subjects to focus on t
Essential Clinical Oral Biology is an accessible guide to oral biology, introducing the scientific knowledge necessary to succeed in clinical practice. Student-friendly layout with clinical photographs throughout Each chapter has clearly defined key topics and learning objectives Covers the essentials: what you need to know and why Companion website featuring interactive MCQs, teaching presentations and downloadable images
This second edition volume presents a selection of cellular and molecular techniques that can be adapted to cover a range of applications and diseases. The book is divided into three sections: saliva and oral diseases, molecular biosciences, and cell and tissues. The first section contains chapters that discuss proteomic analyses by mass spectrometry and NMR-based metabolomics that can be used to not only study saliva, but also to assess other oral fluids such as gingival crevicular fluid. The second section contains chapters that profile oral microbial communities, quantitative real-time PCR, and adhesion of yeast and bacteria to oral surfaces. The third section deals with a range of approaches that enable the behavior of cells and tissues in both health and disease to be analyzed at the molecular level. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Oral Biology: Molecular Techniques and Applications, Second Edition is a useful resource for oral biologists at all levels (students, early career researchers, and experienced veterans), and it provides a ready reference to new techniques and approaches that can be used to answer numerous specific scientific questions that may lead to a deeper understanding and treatments of oral diseases.
A new volume in the successful revision guide series – Master Dentistry - which offers a concise text covering the essentials of oral biology with accompanying self-assessment questions and model answers. Quick reference revision aid for dental students – ideal for exam preparation! Covers the ‘essentials’ of the subject to a level that is expected with the GDC’s curriculum outlined in the First Five Years document. Each chapter provides a brief overview of the topic and lists the essential learning objectives for that area of study. Presents key anatomical, biochemical and physiological material in a useful, integrated, clinically relevant format. Includes extensive self-testing material – true false questions, extended matching questions, picture questions, and essay questions – enabling readers to assess their knowledge and perfect exam techniques. Contains unique, ‘mind-map’ summary sheets to provide crucial information in a pictorial format to further promote learning.
Biochemistry and Oral Biology presents a unique exposition of biochemistry suitable for dental students. It discusses the structural basis of metabolism and the general principles of nutrition. It addresses the soft tissues, hard tissues, and the biology of the mouth. Some of the topics covered in the book are the free radical production; scope of biochemistry; characteristics of atoms; structure and properties of water; molecular building materials; ionization of proteins; affinity chromatography of proteins; structural organization of globular proteins; classification of enzymes; and biochemically important sugar derivatives. The naturally occurring fatty acids are fully covered. The nucleic acid components are discussed in detail. The text describes in depth the energy equivalents of different nutrients. The physiological effects of dietary fiber vitamin D deficiency are completely presented. A chapter is devoted to the alternative methods of fluoride administration and description of vitamins. The book can provide useful information to dental students, and researchers.
This textbook provides a comprehensive overview of the part of dentistry that links basic physiologic and pathophysiologic mechanisms to frequently encountered problems in dental practice. Themes that are covered include the structure and function of the cells of oral mucosa, the biology of bone, the functions of oral mucosa, some important aspects on oral microbial flora and biofilms and finally the current principles on mastication, swallowing and speech. the knowledge of basic sciences is essential in oral biology, helping to understand the nature and behavior of cells, tissues and organs in health and disease. It is an easy-to-read, relatively brief but a comprehensive Ebook appropriate for undergraduate and graduate dental students as well as for practicing clinicians.
Saliva is essential for oral health and influences all events in the mouth. A deficiency of saliva can have devastating consequences. Therefore, it is important to have a book about the basic tissue mechanisms involved in the secretion of saliva, based on an holistic approach. With such an aim in mind, this book contains chapters covering the histological basis for secretion, electrophysiological events, electrolyte and water secretion, protein synthesis and secretion, bloodflow, capillary dynamics, myoepithelial activity, glandular permeability, hormonal influences, including the effects of diabetes, and the synthesis and secretion of IgA in man. The chapters have been written by international experts in the field, who present balanced accounts of their subjects. The secretory mechanisms described in this book have a far-reaching impact beyond the salivary field and have applicability to all forms of exocrine secretion. Salivary glands offer many advantages for experimental study of these phenomena since they can be tested more precisely than most other glands, having ducts that can readily be cannulated for assessing the secretion. As a single-source of up-to-date data, this book will benefit doctors and dentists, and anyone interested in secretory phenomena, including physiologists, biochemists and cell biologists. It not only brings together all available data on this subject, as it stands at the turn of the century, but also lays down a sound platform of knowledge on which further investigations can be based.
Developmental Aspects of Oral Biology assembles within one volume selected contributions from highly competent investigators currently engaged in research on developmental problems in oral tissues. The primary objective of this book is to facilitate rapid and lucid communication among researcher, teacher, student, and the practitioner interested in oral tissues and oral diseases. This is best accomplished by providing critical surveys of discussions of the state of knowledge or concepts in relevant areas of biology that relate to development, development in terms of embryogenesis, prenatal growth and development, maturation, senescence, and developmental aberrations which manifest themselves as oral pathology. The book begins with a study on the nutritional aspects of embryogenesis. Separate chapters then cover the molecular biology of developing systems; immunological determinants in development; and the migration, interaction, and early differentiation of orofacial tissues. Subsequent chapters deal with topics such as the development of the primary and secondary palate and the taste buds; tissue interaction during in vitro odontogenesis; matrix development in mineralizing tissues; and macromolecular interactions in the connective tissues of the periodontium.
Cleft lip and palate is a complex, multifactorial and relatively common craniofacial disorder, which arises because of disrupted facial development in the embryo. The manifestations of this condition can be life-long and associated with significant morbidity. In the last decade, progress has been made in our understanding of how clefts of the lip and palate arise in human populations, and laboratory studies are beginning to elucidate the molecular mechanisms that control development of the lip and palate. In addition, advances in surgical and medical care, and long-term rehabilitation are improving outcome and quality of life for affected individuals. Written by international experts in their respective fields, this publication covers in detail the epidemiology and genetic basis of cleft lip and palate, the developmental biology of lip and palate formation and provides current concepts in the management of patients affected by this condition. Thus, the book provides a contemporary overview of the epidemiology, aetiology and treatment of cleft lip and palate, and will be of use to a wide range of individuals, including students, biologists and clinicians, who have an interest in this subject.
Our understanding of the etiopathology of periodontal disease has changed greatly over the last decade. The huge diversity of species within the microbial biofilm and the enormous multi-layered complexity of the innate, inflammatory and adaptive immune responses generated in response to it warrant study and discussion. Comprising reviews from renowned experts in the field, this book presents a comprehensible overview of this exciting and pertinent subject matter. It provides new insights into the structure and composition of subgingival biofilms and the nature of the extracellular matrix. Further, a summary of current understanding of subgingival microbial diversity and an overview of experimental models used to dissect the functional characteristics of subgingival communities are presented. Other articles discuss the innate cellular and neutrophil responses to the periodontal biofilm. The role of antimicrobial peptides in the host response to biofilm bacteria and modern approaches to nonsurgical biofilm management are also discussed. Finally, this volume addresses advances in antibiotic use and proposes a paradigm shift in the pharmacological approach to periodontal disease management.
Saliva is essential for oral health and influences all events in the mouth. In 1850 Ludwig discovered that autonomic nerve impulses evoke salivary secretion and all work since has shown that the nerves normally control the flow and protein output of saliva. This publication, written by international experts, is the first one devoted to the neuroglandular mechanisms of this control. The book lays a sound platform of knowledge to all with an interest in and around the mouth including dentists, doctors, pharmacologists, biochemists and cell biologists as well as neurobiologists working on autonomic nerve activities.