This new book provides a unified, in-depth, readable introduction to the multipredictor regression methods most widely used in biostatistics: linear models for continuous outcomes, logistic models for binary outcomes, the Cox model for right-censored survival times, repeated-measures models for longitudinal and hierarchical outcomes, and generalized linear models for counts and other outcomes. Treating these topics together takes advantage of all they have in common. The authors point out the many-shared elements in the methods they present for selecting, estimating, checking, and interpreting each of these models. They also show that these regression methods deal with confounding, mediation, and interaction of causal effects in essentially the same way. The examples, analyzed using Stata, are drawn from the biomedical context but generalize to other areas of application. While a first course in statistics is assumed, a chapter reviewing basic statistical methods is included. Some advanced topics are covered but the presentation remains intuitive. A brief introduction to regression analysis of complex surveys and notes for further reading are provided.
This book presents a broad range of statistical techniques to address emerging needs in the field of repeated measures. It also provides a comprehensive overview of extensions of generalized linear models for the bivariate exponential family of distributions, which represent a new development in analysing repeated measures data. The demand for statistical models for correlated outcomes has grown rapidly recently, mainly due to presence of two types of underlying associations: associations between outcomes, and associations between explanatory variables and outcomes. The book systematically addresses key problems arising in the modelling of repeated measures data, bearing in mind those factors that play a major role in estimating the underlying relationships between covariates and outcome variables for correlated outcome data. In addition, it presents new approaches to addressing current challenges in the field of repeated measures and models based on conditional and joint probabilities. Markov models of first and higher orders are used for conditional models in addition to conditional probabilities as a function of covariates. Similarly, joint models are developed using both marginal-conditional probabilities as well as joint probabilities as a function of covariates. In addition to generalized linear models for bivariate outcomes, it highlights extended semi-parametric models for continuous failure time data and their applications in order to include models for a broader range of outcome variables that researchers encounter in various fields. The book further discusses the problem of analysing repeated measures data for failure time in the competing risk framework, which is now taking on an increasingly important role in the field of survival analysis, reliability and actuarial science. Details on how to perform the analyses are included in each chapter and supplemented with newly developed R packages and functions along with SAS codes and macro/IML. It is a valuable resource for researchers, graduate students and other users of statistical techniques for analysing repeated measures data.
"Thoroughly revised and updated, the second edition of Intuitive Biostatistics retains and refines the core perspectives of the previous edition: a focus on how to interpret statistical results rather than on how to analyze data, minimal use of equations, and a detailed review of assumptions and common mistakes. Intuitive Biostatistics, Completely Revised Second Edition, provides a clear introduction to statistics for undergraduate and graduate students and also serves as a statistics refresher for working scientists. New to this edition: Chapter 1 shows how our intuitions lead us to misinterpret data, thus explaining the need for statistical rigor. Chapter 11 explains the lognormal distribution, an essential topic omitted from many other statistics books. Chapter 21 contrasts testing for equivalence with testing for differences. Chapters 22, 23, and 40 explore the pervasive problem of multiple comparisons. Chapters 24 and 25 review testing for normality and outliers. Chapter 35 shows how statistical hypothesis testing can be understood as comparing the fits of alternative models. Chapters 37 and 38 provide a brief introduction to multiple, logistic, and proportional hazards regression. Chapter 46 reviews one example in great depth, reviewing numerous statistical concepts and identifying common mistakes. Chapter 47 includes 49 multi-part problems, with answers fully discussed in Chapter 48. New "Q and A" sections throughout the book review key concepts"--Provided by publisher.
The identification and use of surrogate endpoints, i.e., measures that can replace or supplement other endpoints in evaluations of experimental treatments or other interventions, is a general strategy that has stimulated both enthusiasm and scepticism. This book offers a balanced account on this controversial topic.
This text on survival analysis provides a straightforward and easy-to-follow introduction to the main concepts and techniques of the subject. It is based on numerous courses given by the author to students and researchers in the health sciences and is written with such readers in mind. Throughout, there is an emphasis on presenting each new topic motivated with real examples of a survival analysis investigation, and then presenting thorough analyses of real data sets. Each chapter concludes with practice exercises to help readers reinforce their understanding of the concepts covered in the chapter.
In dem Band beschreiben die Autoren erstmals klassische Regressionsansätze und moderne nicht- und semiparametrische Methoden in einer integrierten und anwendungsorientierten Form. Um Lesern die Analyse eigener Fragestellungen zu ermöglichen, demonstrieren sie die praktische Anwendung der Konzepte und Methoden anhand ausführlicher Fallstudien. Geeignet für Studierende der Statistik sowie für Wissenschaftler und Praktiker, zum Beispiel in den Wirtschafts- und Sozialwissenschaften, der Bioinformatik und -statistik, Ökonometrie und Epidemiologie.
This book provides a practical introduction to analyzing ecological data using real data sets. It features 17 case studies covering topics ranging from terrestrial ecology to marine biology and can be used as a template for a reader’s own data analysis.
Entdecken Sie mit "Statistik für Dummies" Ihren Spaß an der Statistik und werfen Sie einen Blick hinter die Kulissen der so beliebten Manipulation von Zahlenmaterial! Deborah Rumsey zeigt Ihnen das nötige statistische Handwerkszeug wie Stichprobe, Wahrscheinlichkeit, Bias, Median, Durchschnitt und Korrelation. Sie lernen die verschiedenen grafischen Darstellungsmöglichkeiten von statistischem Material kennen und werden über die unterschiedlichen Methoden der Auswertung erstaunt sein. Schärfen Sie mit diesem Buch Ihr Bewusstsein für Zahlen und deren Interpretation, so dass Ihnen keiner mehr etwas vormachen kann!
This textbook teaches crucial statistical methods to answer research questions using a unique range of statistical software programs, including MINITAB and R. This textbook is developed for undergraduate students in agriculture, nursing, biology and biomedical research. Graduate students will also find it to be a useful way to refresh their statistics skills and to reference software options. The unique combination of examples is approached using MINITAB and R for their individual strengths. Subjects covered include among others data description, probability distributions, experimental design, regression analysis, randomized design and biological assay. Unlike other biostatistics textbooks, this text also includes outliers, influential observations in regression and an introduction to survival analysis. Material is taken from the author's extensive teaching and research in Africa, USA and the UK. Sample problems, references and electronic supplementary material accompany each chapter.
A book/disk text for a one- or two-semester course in basics of applied biostatistics. Learning features include summaries of formulas and terms, exercises, and statistical tables. This third edition reduces emphasis on methods of computation, and concentrates more on the rationale and utility of v
An all-in-one review for the cardiology boards – complete with a CD-ROM with 600+ board-style questions McGraw-Hill Specialty Board Review: Cardiology is the ideal cardiology primer – whether you’re studying for board certification or seeking a thorough review of current thinking in cardiovascular medicine. You’ll find everything you need in one all-inclusive package: a CD-ROM with hundreds of board-style questions and thorough explanations; bulleted practical points at the beginning of each chapter; tables, charts, graphs, references and suggested reading; and more than 1000 illustrations – many in full color. Everything you need to pass the boards or keep abreast of this ever-changing field:“br/> Coverage of all specialty topics in general cardiology –- from prevention and imaging to heart failure Companion CD-ROM with 600+ questions in the exam style with detailed answer explanations Streamlined bulleted presentation and numerous tables and charts Suggested Reading or references at the end of each chapter Content that reflects mainstream thinking rather than a limited single-center perspective Content that spans all major areas of Cardiology: General Topics, Pulmonary, Preventive Cardiology, Coronary Artery Disease, Acute Coronary Syndrome, Intervention, Imaging, Heart Failure, Electrophysiology, Valvular Heart Disease, Congenital Heart Disease, Aorta and Vascular Diseases, Special Topics (Cardiac Tumors, HIV and Heart, Infective Endocarditis).
This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work. This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.
Aus den Besprechungen: "Unter den zahlreichen Einführungen in die Wahrscheinlichkeitsrechnung bildet dieses Buch eine erfreuliche Ausnahme. Der Stil einer lebendigen Vorlesung ist über Niederschrift und Übersetzung hinweg erhalten geblieben. In jedes Kapitel wird sehr anschaulich eingeführt. Sinn und Nützlichkeit der mathematischen Formulierungen werden den Lesern nahegebracht. Die wichtigsten Zusammenhänge sind als mathematische Sätze klar formuliert." #FREQUENZ#1
This new edition of the book will be produced in two versions. The textbook will include a CD-Rom with two videotaped lectures by the authors. This book translates biostatistics in the health sciences literature with clarity and irreverence. Students and practitioners alike, applaud Biostatistics as the practical guide that exposes them to every statistical test they may encounter, with careful conceptual explanations and a minimum of algebra. What's New? The new Bare Essentials reflects recent advances in statistics, as well as time-honored methods. For example, "hierarchical linear modeling" which first appeared in psychology journals and only now is described in medical literature. Also new, is a chapter on testing for equivalence and non-inferiority. As well as a chapter with information to get started with the computer statistics program, SPSS. Free of calculations and jargon, Bare Essentials speaks so plainly that you won't need a technical dictionary. No math, all concepts. The objective is to enable you to determine if the research results are applicable to your own patients. Throughout the guide, you'll find highlights of areas in which researchers misuse or misinterpret statistical tests. We have labeled these "C.R.A.P. Detectors" (Convoluted Reasoning and Anti-intellectual Pomposity), which help you to identify faulty methodology and misuse of statistics.
Gegenstand des Werkes sind Analyse und Modellierung von Zeitreihen. Es wendet sich an Studierende und Praktiker aller Disziplinen, in denen Zeitreihenbeobachtungen wichtig sind.