The Immune System, Fourth Edition emphasizes the human immune system and presents immunological concepts in a coherent, concise, and contemporary account of how the immune system works. Written for undergraduate, medical, veterinary, dental, and pharmacy students, it makes generous use of medical examples to illustrate points. This classroom-proven textbook offers clear writing, full-color illustrations, and section and chapter summaries that make the book accessible and easily understandable to students. The Fourth Edition is a major revision that brings the content up-to-date and improves clarity. Based on user feedback, there is now increased continuity and connectivity between chapters.
Understand all the essential concepts in immunology with this book that provides you with an up-to-date, accessible introduction to the workings of the human immune system. This book enables you to efficiently master the immunology information you need through clinically focused content, logically organized by mechanism. You can apply what you have learned to real-world situations by referencing the appendix of clinical cases. It can enhance your learning with the help of numerous full-color illustrations and useful tables, as well as summary boxes, review questions, and a glossary of immunology terms. -- Publisher description.
How the Immune System Works has helped thousands of students understand what’s in their big, thick, immunology textbooks. In his book, Dr. Sompayrac cuts through the jargon and details to reveal, in simple language, the essence of this complex subject. In fifteen easy-to-read chapters, featuring the humorous style and engaging analogies developed by Dr. Sompayrac, How the Immune System Works explains how the immune system players work together to protect us from disease – and, most importantly, why they do it this way. Rigorously updated for this fifth edition, How the Immune System Works includes the latest information on subjects such as vaccines, the immunology of AIDS, and cancer. A highlight of this edition is a new chapter on the intestinal immune system – currently one of the hottest topics in immunology. Whether you are completely new to immunology, or require a refresher, How the Immune System Works will provide you with a clear and engaging overview of this fascinating subject. But don’t take our word for it! Read what students have been saying about this classic book: "What an exceptional book! It's clear you are in the hands of an expert." "Possibly the Best Small Text of All Time!" "This is a FUN book, and Lauren Sompayrac does a fantastic job of explaining the immune system using words that normal people can understand." "Hands down the best immunology book I have read... a very enjoyable read." "This is simply one of the best medical textbooks that I have ever read. Clear diagrams coupled with highly readable text make this whole subject easily understandable and engaging." Now with a brand new website at www.wiley.com/go/sompayrac featuring Powerpoint files of the images from the book
Keep abreast of the latest advances in this complex field with the 5th Edition of Clinical Immunology: Principles and Practice. This substantially revised edition by Drs. Robert R. Rich, Thomas A. Fleisher, William T. Shearer, Harry W. Schroeder, Jr., Anthony J. Frew, and Cornelia M. Weyand, offers authoritative guidance from some of the most respected global leaders in immunology, helping you navigate today’s latest knowledge and evidence-based practices that result in improved patient care. This trusted resource features sweeping content updates, rewritten chapters, a highly clinical perspective, and an easy-to-use organization designed to enhance your diagnosis and management skills in daily practice. Includes new chapters on the Microbiota in Immunity and Inflammation, Immune Responses to Fungi, and Genetics and Genomics of Immune Response. Features extensive revisions to many chapters, including the Major Histocompatibility Complex, Multiple Sclerosis, Diabetes and Related Autoimmune Diseases, Biologic Modifiers of Inflammation and Tumor Immunotherapy. Covers hot topics such as the role of genetics and genomics in immune response and immunologic disease, atherosclerosis, recurrent fever syndromes, aging and deficiencies of innate immunity, the role of microbiota in normal immune system development and the pathogenesis of immunologic and inflammatory diseases, and novel therapeutics. Addresses notable advances in key areas such as the importance of the microbiota to normal immune system development and to the pathogenesis of immunologic and inflammatory diseases; relationships between the innate and adaptive immune systems; progress in rapid and cost-effective genomics; cell signaling pathways and the structure of cell-surface molecules; and many more. Summarizes promising research and development anticipated over the next 5-10 years with "On the Horizon" boxes and discussion of translational research.
Psychoneuroimmunology, Second Edition presents reports on the relationship between the nervous and immune systems. The book is divided into four sections. The first section details the role of neural structures and neurotransmitter signals in communication with the immune system. It documents the extensive neural connections with organs of the immune system; the dynamics of noradrenergic sympathetic innervation of spleen and thymus; and the evidence for immune signaling of the CNS. Part II elaborates the role of hormones in the modulation of immune functions; the basis for bidirectional communication between the neuroendocrine and immune systems; and the potential physiological implications of these neuroendocrine-immune system interactions. The third part addresses behavioral influences on immune response; the effects of conditioning, stress and social interactions in modulating immune responses; and the behavioral consequences of experimentally altered or genetically determined immunologic states. The final section presents the effects of psychosocial factors on immune responses and the potential impact of behavioral interventions in modulating immunity in healthy human subjects and in patients with AIDS. Neuroscientists, endocrinologists, and immunologists will find the book interesting.
Our immune system is a complex network of cells continually battling against a barrage of attacks from our environment, quite literally to save our lives. But what protects us from the potentially life-threatening microorganisms that surround us every day? Infection and Immunity describes the main causes of infection that our bodies have to battle against - from bacteria to viruses, fungi to protozoa - and explains the intricate andfascinating ways in which we respond, from detection of potentially dangerous organisms to their ultimate elimination. Presenting a fully-rounded, well-balanced overview of the field,the book also explains how diseases spread, and what measures we can take to control this spread - from vaccination to increasing awareness through public health initiatives.
As the amount of information in biology expands dramatically, it becomes increasingly important for textbooks to distill the vast amount of scientific knowledge into concise principles and enduring concepts.As with previous editions, Molecular Biology of the Cell, Sixth Edition accomplishes this goal with clear writing and beautiful illustrations. The Sixth Edition has been extensively revised and updated with the latest research in the field of cell biology, and it provides an exceptional framework for teaching and learning. The entire illustration program has been greatly enhanced.Protein structures better illustrate structure–function relationships, icons are simpler and more consistent within and between chapters, and micrographs have been refreshed and updated with newer, clearer, or better images. As a new feature, each chapter now contains intriguing openended questions highlighting “What We Don’t Know,” introducing students to challenging areas of future research. Updated end-of-chapter problems reflect new research discussed in the text, and these problems have been expanded to all chapters by adding questions on developmental biology, tissues and stem cells, pathogens, and the immune system.
Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. Provides solid scientific basis to our understanding of the associations between the brain and the immune system the importance of these connections Presents coherent development from cellular and molecular neuroimmune communication to social and health considerations, including psychological intervention Addresses the theory that there is a neurobiology of the immune system
Immunology at a Glance provides a user-friendly overview of the body’s defence mechanisms. Ideal from day one of a medical, biomedical or life science course, the text begins with a basic overview of both adaptive and innate immunity, before progressing to applied immunological concepts, which look at what happens when things go wrong, and how, in clinical medicine, each body system can be affected by immunity. Each double-page spread corresponds to a typical lecture and diagrammatically summarises core concepts in immunology, through accessible schematic diagrams on left-hand pages, with key points concisely summarised on the right-hand page. There are also self-assessment essay questions so you can test your knowledge. New for this 10th edition: Thoroughly updated and reorganised chapters offer greater clarity and easier understanding for those new to the subject New chapters on cytokine receptors and ‘Immunology in the Laboratory’ A completely re-written section on autoimmunity A brand new companion website featuring self-assessment questions and PowerPoint slides of images from the book, ideal for teaching and revision at www.ataglanceseries.com/immunology Immunology at a Glance is the ideal companion for anyone about to start a new course in immunology and will appeal to medical and biomedical science students. Perfect for exam preparation, it provides the concepts and frameworks you need to succeed in your exam.
Since publication of the 4th Edition of The Autoimmune Diseases in 2006, the understanding of the immune mechanisms underlying autoimmunity and autoimmune disease has significantly deepened and broadened. This fully revised 5th Edition incorporates new material and combines common themes underlying inductive and effector mechanisms and therapies that relate generally to the autoimmune disorders. It discusses the biological basis of disease at genetic, molecular, cellular, and epidemiologic levels and includes expanded coverage of autoinflammatory disease and autoimmune responses to tumors. Gives a thorough and an important overview on the entire field, framing individual disease chapters with information that compares and contrasts each disorder and therapy Provides thorough, up-to-date information on specific diseases, along with clinical applications, in an easily found reference for clinicians and researchers interested in certain diseases Keeps readers abreast of current trends and emerging areas in the field Ensures that content is not only up-to-date, but applicable and relevant
Comprehensive yet concise and easy to read, this updated edition of Immunology for Medical Students effectively explains complex immunology topics and their relevance in clinical practice. Boasting just the right amount of detail for today's busy medical student, it delivers state-of-the-art coverage of the latest scientific and clinical knowledge in the field. Detailed and explanatory illustrations, combined with clinically relevant examples and cases, offer a unique understanding of the human immune system and its role in protecting us from disease. Designed with a clear focus on the needs of medical students. Includes overview illustrations at the beginning of each chapter, as well as illustrations with dialogue boxes. Immunology icons are repeated throughout the text, accompanied by a helpful Icon Key. Detailed clinical cases demonstrate real-world applications. Technical boxes point out important scientific advances. End-of-chapter checklists of learning points facilitate review. Features 17 new clinical boxes as well as critical revisions to 25 of the clinical boxes featured in the previous edition, providing relevant, practical examples of cases commonly encountered in day-to-day practice. Presents new material on T Cell Subsets, the molecular and cellular processes involved in their selection and differentiation, and how this knowledge is already translating into clinical developments. Includes a brand-new chapter titled Regulation of the Immune System.
The newly revised edition of this work provides an up-to-date description of the mechanisms of infection and disease production in a clear and logical manner. Dealing in an integrated manner with all microorganisms, the factors common to all infectious diseases are set out. Molecular biology, pathology, and immunology are brought together to explain how an infectious agent causes disease, and how the body reacts to it. Attachment to and entry of microorganisms Events occurring immediately after entry The encounter of the microbe with the phagocytic cell The spread of microbes through the body The immune response to infection Microbial strategies in relation to the immune response Mechanisms of cell and tissue damage Recovery from infection Failure to eliminate the microbe Host and microbial factors influencing susceptibility Vaccines
Uveitis is the comprehensive reference you need for a balanced approach to basic science and clinical application. Robert B. Nussenblatt and Scott M. Whitcup provide a cohesive and integrated discussion of the topic, covering everything from the role of surgery to AIDS to anterior uveitis and more. This new edition even includes full color throughout with 400 photographs and illustrations. Comprehensive yet readable, this resource packs everything you need in patient evaluation and management to achieve optimal results. Covers the medical, pharmacological, and surgical treatment of uveitis to serve as a complete overview of all uveitis related information. Features multiple chapters on diagnostic approach to help you overcome challenges in making accurate diagnoses. Provides additional information on inflammatory eye diseases in chapters on scleritis, masquerade syndromes, and the role of inflammation in other ocular diseases for more comprehensive coverage. Includes illustrated case studies to supplement major clinical points and provide insight into real situations that you can apply in practice. Highlights important information in key points boxes that make it easy to locate crucial points on each topic. Features significant updates to the chapters on the role of surgery in the patient with uveitis, acquired immune deficiency syndrome, anterior uveitis, white dot syndromes, and masquerade syndromes. Covers advancements and new developments on all aspects of uveitis including new medical and surgical treatments. Presents photographs in full color to better prepare you for actual clinical diagnosis.
Lecture Notes on Immunology is a best-selling core text, providing a concise introduction to immunology. It focuses on basic science but informs the reader of the clinical relevance where appropriate for a clear understanding of the cells, molecules and processes of the immune system. The book has been thoroughly updated to include new sections on: the interaction between innate and adaptive immunity; the roles and regulation of T-cell subpopulations, cytokines and adhesion molecules; genetic and environmental factors affecting susceptibility to infection, immunodeficiency and atopic disease. Clear and concise: no waffle, easy to use for revision. Written by a scientist and a scientist physician, resulting in a balanced text, relevant to medical students and allied health students. Takes an integrated approach combining basic science with clinical information: of value to students who need to know the clinical relevance of the basic science.
Master the latest in the ever-evolving field of histology with the in-depth and visually engaging Stevens and Lowe’s Human Histology. Intended as a complete introduction to the subject, this updated medical reference book incorporates clinical correlations and case studies with the basic information that's essential for students to thrive in the medical environment. Learn from an easy-to-read writing style and well-designed, full-color layout to present of all histology's need-to-know content. Conveniently access important information through a design that sets off the key laboratory, clinical, and high-level scientific material in boxes. Take advantage of an increased amount of clinical content and photos. Master the basics of the field with an enhanced focus on cell biology. Quickly review important information with reviews available at the end of each chapter, Key Facts boxes throughout the chapters, and MCQs in the text. Easily visualize complex procedures and concepts with nearly 900 illustrations, photos, and graphics. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability.
The perfect balance of theory and practice! Here’s the must-have information you need to understand the essential principles of immunology and to master the serology techniques most commonly used in the laboratory. Easy-to-read, student-friendly coverage focuses on the direct application of theory to clinical laboratory practice, preparing you for the real world in which you will practice. The 4th Edition of this popular text has been completely updated and revised throughout to reflect the latest advances in the field. A brand-new full-color layout makes the content easier to understand than ever before.
The comparative approach to immunology can be traced to the era of Pasteur and Metchnikov in which observations regarding foreign recognition in invertebrates was a factor in the develop ment of the principal concepts that created the foundation of what now is the broad field of immunology. With each major experimental and conceptual breakthrough, the classical, albeit essential, question has been asked "are the immune systems of phylogenetically primitive vertebrates and invertebrates similar to that of mammals?" Somewhat surprisingly for the jawed verte brates, the general answer has been a qualified form of "yes", whereas for agnathans and invertebrate phyla it has been "no" so far. The apparent abruptness in the appearance of the immune system of vertebrates is linked to the introduction of the somatic generation of the diversity of its antigen specific receptors. Therefore the questions regarding the origin and evolution of the specific immune system revolve around this phenomenon. With respect to the origin of the system (aside from the or igin of the rearranging machinery itself, the study of which is still in its infancy) one can ask questions about the cellular and mo lecular contexts in which the mechanism was introduced.
The new edition of this highly successful book continues to offer readers everything they require to gain a full understanding of microbiology as it relates to modern dental practice. The rich combination of easy-to-read text together with the extensive artwork programme makes Essential Microbiology for Dentistry the first choice of microbiology textbook for many students of dentistry worldwide. Comprehensive coverage of the subject area makes the book suitable for all aspects of the curriculum Almost 300 tables and illustrations present clinical, diagnostic and practical information in an easy-to-follow manner Contains ‘Key Facts’ boxes to act as useful aide-mémoires Self-assessment sections at the end of each chapter allow students to assess their understanding in key areas of knowledge Addresses the subject on a strictly ‘need-to-know for the dentist’ approach [e.g. only salient bacteria are included with thumbnail sketches of viruses and fungi] Contains a detailed - and now expanded - glossary and abbreviations list Contains the latest organism nomenclature and information regarding unculturable bacteria and novel molecular technology Includes a highly expanded section on oral biofilms and their relevance to systemic disease such as heart disease, diabetes, adverse pregnancy outcomes and nosocomial pneumonia Contains a brand new section on oral immunology – prepared by guest authors – as relevant to dentistry Contains a new section on the microbiology of perimplantitis Presents a fully revised and expanded section on infection control in dentistry encompassing British and American guidelines